Endothelin-1 concentration is increased in the aqueous humour of patients with exfoliation syndrome

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Endothelin-1 concentration is increased in the aqueous humour of patients with exfoliation syndrome.

BACKGROUND /aim: Endothelin 1 (ET-1) is considered the most potent vasoconstrictor in the body and the eye. This molecule may play a significant role in the pathobiology of exfoliation syndrome (XFS), a disorder characterised by a progressive iris vasculopathy. The purpose of this study was to investigate the concentration of ET-1 in the aqueous humour of cataract patients with and without XFS....

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8-Isoprostaglandin F2a and ascorbic acid concentration in the aqueous humour of patients with exfoliation syndrome.

BACKGROUND/AIMS The authors investigated the concentrations of 8-isoprostaglandin F(2a), a marker of oxidative stress in vivo, and ascorbic acid, a protectant against oxidative damage, in the aqueous humour of patients with exfoliation syndrome (XFS) and cataract and compared the results with those in age matched patients with cataract, but without XFS, to determine whether XFS is associated wi...

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LABORATORY SCIENCE 8-Isoprostaglandin F2a and ascorbic acid concentration in the aqueous humour of patients with exfoliation syndrome

Background/aim: The authors investigated the concentrations of 8-isoprostaglandin F2a, a marker of oxidative stress in vivo, and ascorbic acid, a protectant against oxidative damage, in the aqueous humour of patients with exfoliation syndrome (XFS) and cataract and compared the results with those in age matched patients with cataract, but without XFS, to determine whether XFS is associated with...

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Concentration of clobetasone butyrate in aqueous humour.

The concentrations of clobetasone butyrate and betamethasone were measured in aqueous humour of patients undergoing cataract extraction 12.5 to 18.5 hours after application into the lower conjunctival sac of an ointment containing 0.1% of the steroid. Samples were assayed from 10 patients receiving clobetasone butyrate and 13 patients receiving betamethasone phosphate. There were measurable con...

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the levels of klotho and endothelin-1 in aqueous humor and plasma of patients with pseudoexfoliation syndrome

purpose: to investigate the levels of klotho and endothelin-1(et-1) in plasma and aqueous humor in patients with pseudoexfoliation syndrome (pes). methods: fifteen individuals with pes and 15 age-matched subjects without pes who were scheduled for cataract extraction participated in the study. samples of aqueous humor and peripheral blood were taken in the operating room just before cataract su...

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ژورنال

عنوان ژورنال: British Journal of Ophthalmology

سال: 2004

ISSN: 0007-1161

DOI: 10.1136/bjo.2003.028290